Since the FDA pulled every 10-15% minoxidil and anything containing azelaic acid, the golden days of minoxidil products with added DHT blocking substances are over, and a lot of people went back to using regular 5% minoxidil.
They just are not as effective anymore, but supposedly, they are now safer.
Lipogaine used to have 5% azelaic acid. It later switched to a natural alternative Azetinol to minimize the possible scalp itchiness caused by azelaic acid.
Besides Azetinol, it also contains other ingredients that are proven to prevent hair follicle shrinkage by DHT. For instance; saw palmetto extract, oleic acid, linolenic acid, beta-sitosterol, etc.
Lipogaine is pricier compared to regular 5% minoxidil brands. If you can afford increased price tag, it’s probably a good idea. The added DHT-blocking ingredients will give you a boost, but they can’t compare to finasteride.